Hookworm infections and anaemia: a literature review accounting for malaria endemicity

Infection with soil-transmitted helminths (STH) is thought to result in several impairing morbidities including iron-deficiency anaemia, particularly in the case of hookworm. However, while there are systematic reviews and experimental studies supporting this association, other studies failed to demonstrate this correlation. The difference in finding may be due to the existence of confounding factors, including malaria, which is a well-accepted cause of iron-deficiency anaemia. The aim of this project is to summarize the association between hookworm infection and anaemia in malaria endemic vs non-endemic regions.